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The ocular mathematical virtual simulator: A validated multiscale model for hemodynamics and biomechanics in the human eye.

Authors :
Sala, Lorenzo
Prud'homme, Christophe
Guidoboni, Giovanna
Szopos, Marcela
Harris, Alon
Source :
International Journal for Numerical Methods in Biomedical Engineering. Feb2024, Vol. 40 Issue 2, p1-34. 34p.
Publication Year :
2024

Abstract

We present our continuous efforts from a modeling and numerical viewpoint to develop a powerful and flexible mathematical and computational framework called Ocular Mathematical Virtual Simulator (OMVS). The OMVS aims to solve problems arising in biomechanics and hemodynamics within the human eye. We discuss our contribution towards improving the reliability and reproducibility of computational studies by performing a thorough validation of the numerical predictions against experimental data. The OMVS proved capable of simulating complex multiphysics and multiscale scenarios motivated by the study of glaucoma. Furthermore, its modular design allows the continuous integration of new models and methods as the research moves forward, and supports the utilization of the OMVS as a promising nonā€invasive clinical investigation tool for personalized research in ophthalmology. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20407939
Volume :
40
Issue :
2
Database :
Academic Search Index
Journal :
International Journal for Numerical Methods in Biomedical Engineering
Publication Type :
Academic Journal
Accession number :
175447232
Full Text :
https://doi.org/10.1002/cnm.3791