Back to Search
Start Over
A self-healing coating with embedding of polyphenols on magnesium: Towards enhanced corrosion protection for biodegradable vascular implants.
- Source :
-
Chemical Engineering Journal . Feb2024, Vol. 482, pN.PAG-N.PAG. 1p. - Publication Year :
- 2024
-
Abstract
- • A polyphenol embedded PTMC coating was prepared by solvent volatilization method. • The embedded polyphenol could complex with Mg2+ to promote corrosion resistance. • The coating had self-healing ability for scratch and polarization breakdown. • The coating improves the biocompatibility of Mg. Biodegradable magnesium-based vascular stent has become a research hotspot in the field of interventional medical engineering. However, the rapid degradation rate and inadequate biocompatibility of magnesium-based vascular stents often lead to implant failure in biomedical applications. It is of great research significance to slow down the degradation rate of magnesium-based stents and impart them with multifunctional bioactivity through surface modification. In this study, a self-healing coating with embedding of polyphenols is developed to create on the surface of magnesium towards corrosion protection and biocompatibility. By controlling and studying the self-healing responsiveness of the coating, the corrosion resistance under vascular implantation conditions is investigated. The embedding of polyphenols endows the interface a self-healing capability, which might be drawn as the chelation between phenol/metal ions and the formation of intermolecular connection between each of the chelating units which ultimately cause enhanced corrosion protection. Furthermore, the evaluation of biocompatibility indicates that the polyphenol-loaded polymer layer shows good biocompatibility, which is beneficial for the repair of the vascular microenvironment. These results suggest significant potential applications of this composite coating in magnesium-based vascular stents. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13858947
- Volume :
- 482
- Database :
- Academic Search Index
- Journal :
- Chemical Engineering Journal
- Publication Type :
- Academic Journal
- Accession number :
- 175458660
- Full Text :
- https://doi.org/10.1016/j.cej.2024.149020