Design of an Artificial Peptide Inspired by Transmembrane Mitochondrial Protein for Escorting Exogenous DNA into the Mitochondria to Restore their Functions by Simultaneous Multiple Gene Expression (Adv. Funct. Mater. 8/2024).

In the article "Design of an Artificial Peptide Inspired by Transmembrane Mitochondrial Protein for Escorting Exogenous DNA into the Mitochondria to Restore their Functions by Simultaneous Multiple Gene Expression," researchers Keiji Numata and his team discuss their achievement in using an artificial peptide to deliver genes to the mitochondria. This peptide-based delivery carrier selectively targets the mitochondria and allows for the efficient expression of multiple genes in cells with mitochondrial dysfunction. The study contributes to the advancement of mitochondrial engineering technologies and their potential application in treating mitochondrial diseases. [Extracted from the article]