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Role of endoscopic ultrasound-guided tissue acquisition for the diagnosis of gastric wall thickening: a retrospective study with meta-analysis.
- Source :
-
Annals of Gastroenterology . 2023, Vol. 36 Issue 6, p605-614. 17p. - Publication Year :
- 2023
-
Abstract
- Background: Tissue acquisition from a thickened gastric wall using biopsy forceps may not always lead to diagnosis, given the submucosal location of the pathology. Endoscopic ultrasound (EUS)-guided tissue acquisition (TA) may serve as a minimally invasive diagnostic tool in such cases. Hence, we aimed to assess the diagnostic outcome and safety of EUS-TA from thickened gastric walls. Methods: Data from patients with gastric wall thickening undergoing EUS-TA at 5 tertiary care centers from August 2020 to August 2022 were retrospectively analyzed. These data were pooled with studies obtained from a comprehensive search of Medline, Embase and Scopus from January 2000 to November 2022 and a meta-analysis was performed. Pooled event rates were calculated using an inverse variance model. Results: The search strategy yielded 13 studies that were combined with data from 30 patients from our centers; a total of 399 patients were included in the analysis. The pooled rate of sample adequacy was 94.1% (95% confidence interval [CI] 90.0-98.2), while the pooled rate of diagnostic accuracy was 91.3% (95%CI 87.0-95.5). The pooled sensitivity and specificity for diagnosing malignant lesions with EUS-TA from gastric wall thickening were 94.8% (95%CI 91.3-97.2) and 100% (95%CI 93.6-100), respectively. There were no reported adverse events in any of the studies. Conclusions: EUS-TA offers a safe and accurate diagnostic modality for the etiological diagnosis of thickened gastric walls. Further research is required to identify the needle type and optimal technique for improving outcomes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ENDOSCOPIC ultrasonography
*NEEDLE biopsy
*GASTRIC outlet obstruction
Subjects
Details
- Language :
- English
- ISSN :
- 11087471
- Volume :
- 36
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Annals of Gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 175587905
- Full Text :
- https://doi.org/10.20524/aog.2023.0831