Phyto-Mediated Green Synthesis of Silver Nanoparticles Using an Aqueous Leaf Extract of Momordica cymbalaria : Antioxidant, Cytotoxic, Antibacterial, and Photocatalytic Properties.

In this study, we biosynthesized the stable silver nanoparticles (AgNPs) from Momordica cymbalaria leaves to evaluate their antioxidant, antibacterial, cytotoxic, and photocatalytic properties. Initially, we screened the bioactive compounds from M. cymbalaria extract using GC-MS. The biosynthesis of Mc-AgNPs was confirmed using instruments, such as UV-visible spectroscopy FT-IR, XRD, SEM with EDX, and HR-TEM analyses. The UV-visible spectrum indicated absorbance at 425 nm. The crystallite size of the M. cymbalaria-stabilized nanoparticles was determined to be 20.14 nm. The morphology and size of the synthesized Mc-AgNPs were confirmed via SEM-EDX and HR-TEM analyses, with a size range from 16 to 22 nm. The synthesized Mc-AgNPs exhibited a photocatalytic yield of 60%. The biosynthesized Mc-AgNPs demonstrated strong antioxidant properties and prominent antibacterial activity against human pathogenic bacteria. The cytotoxicity study revealed that Mc-AgNPs were effective against MCF-7 cells in a dose-dependent manner. The recognized bioactivities confirm that the synthesized Mc-AgNPs act as effective catalysts in oxidation and serve as potent antioxidant, anticancer, and antibacterial agents. [ABSTRACT FROM AUTHOR]