Incidence and risk factors of post-thrombotic syndrome in patients with isolated calf vein thrombosis. Findings from the GARFIELD-VTE registry.

• Isolated distal DVT (IDDVT), which comprise 1/3rd of all lower extremity DVTs is sparsely studied • Prandoni P et.al., 2023, assessed the development of PTS in 745 patients with IDDVT • PTS patients had a higher rate of previous VTE • They were more likely to have chronic heart failure (CHF) and had a lower prevalence of recent surgery • CHF, immobilization and prior DVT and/or PE were associated with increased risk of PTS in IDDVT • Results suggest long-term sequelae are to be expected in 1/5 patients with isolated below-knee DVT • This real-world study allowed the identification of a promising prediction score [ABSTRACT FROM AUTHOR]