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Sleep Disturbances in Early Gestation and the Risks of Hypertensive Disorders of Pregnancy: A Prospective Cohort Study.
- Source :
-
American Journal of Epidemiology . Mar2024, Vol. 193 Issue 3, p479-488. 10p. - Publication Year :
- 2024
-
Abstract
- Maternal poor sleep quality may increase blood pressure during pregnancy, but sound evidence is still limited and inconsistent. To evaluate whether sleep disturbances in early gestation are risk factors for the development of hypertensive disorders of pregnancy, we conducted the Early Life Plan Project from June 2016 to December 2019. Maternal sleep patterns were assessed at 12–16 weeks of gestation by using the Pittsburgh Sleep Quality Index questionnaire. For gestational hypertension and preeclampsia, we estimated adjusted odds ratios (ORs) and 95% confidence intervals (CIs) using multinomial logistic regression models adjusting for potential confounders. Among 5,532 eligible women, we observed that maternal blood pressure in early gestation was significantly higher in women with low sleep efficiency (≤85%), long sleep duration (≥9 hours/night), and snoring. Compared with nonsnorers, snoring in early gestation was independently associated with preeclampsia (OR = 1.72 (95% CI: 1.09, 2.73) for snoring once or twice per week; OR = 2.06 (95% CI: 1.01, 4.31) for snoring 3 or more times per week), particularly for term preeclampsia (OR = 1.79 (95% CI: 1.08, 2.95) and 2.26 (95% CI: 1.03, 4.95), respectively). Results suggest that snoring in early gestation may be a significant risk factor for preeclampsia, with a dose-response pattern. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYPERTENSION risk factors
*RISK factors of preeclampsia
*SLEEP quality
*CONFIDENCE intervals
*FIRST trimester of pregnancy
*SLEEP disorders
*QUESTIONNAIRES
*ODDS ratio
*BLOOD pressure measurement
*SNORING
*LONGITUDINAL method
*DOSE-response relationship in biochemistry
*DISEASE complications
*PREGNANCY
Subjects
Details
- Language :
- English
- ISSN :
- 00029262
- Volume :
- 193
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- American Journal of Epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 175824019
- Full Text :
- https://doi.org/10.1093/aje/kwad223