Distribution and roles of Ligilactobacillus murinus in hosts.

Ligilactobacillus murinus , a member of the Ligilactobacillus genus, holds significant potential as a probiotic. While research on Ligilactobacillus murinus has been relatively limited compared to well-studied probiotic lactic acid bacteria such as Limosilactobacillus reuteri and Lactobacillus gasseri , a mounting body of evidence highlights its extensive involvement in host intestinal metabolism and immune activities. Moreover, its abundance exhibits a close correlation with intestinal health. Notably, beyond the intestinal context, Ligilactobacillus murinus is gaining recognition for its contributions to metabolism and regulation in the oral cavity, lungs, and vagina. As such, Ligilactobacillus murinus emerges as a potential probiotic candidate with a pivotal role in supporting host well-being. This review delves into studies elucidating the multifaceted roles of Ligilactobacillus murinus. It also examines its medicinal potential and associated challenges, underscoring the imperative to delve deeper into unraveling the mechanisms of its actions and exploring its health applications. • Ligilactobacillus murinus is a potential probiotic distributed in the intestines, oral cavity, lungs and vagina. • Ligilactobacillus murinus in the intestine can indicate the degree of health status of the host. • Single Ligilactobacillus murinus is distinguished from Ligilactobacillus murinus in microbial communities. • Ligilactobacillus murinus , emerging as a potential probiotic, is critical for safety assessment and clinical studies when used as probiotic drugs. [ABSTRACT FROM AUTHOR]