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The exceptions that prove the rule—a historical view of bedaquiline susceptibility.
- Source :
-
Genome Medicine . 3/13/2024, Vol. 16 Issue 1, p1-3. 3p. - Publication Year :
- 2024
-
Abstract
- In the accompanying study, Nimmo and colleagues estimated the dates of emergence of mutations in mmpR5 (Rv0678), the most important resistance gene to the anti-tuberculosis drug bedaquiline, in over 3500 geographically diverse Mycobacterium tuberculosis genomes. This provided important insights to improve the design and analysis of clinical trials, as well as the World Health Organization catalogue of resistance mutations, the global reference for interpreting genotypic antimicrobial susceptibility testing results. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MYCOBACTERIUM tuberculosis
*MICROBIAL sensitivity tests
*ANTITUBERCULAR agents
Subjects
Details
- Language :
- English
- ISSN :
- 1756994X
- Volume :
- 16
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Genome Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 176033347
- Full Text :
- https://doi.org/10.1186/s13073-024-01311-w