Synthesis of iron oxide magnetic nanoparticles and chitosan biopolymer in aqueous solutions.

[Display omitted] • Iron oxide magnetic nanoparticles are known for their magnetic properties, which make them useful in various applications such as drug delivery, hyperthermia therapy, and magnetic resonance imaging (MRI). • Chitosan biopolymer, derived from chitin, is widely recognized for its biocompatibility, antibacterial properties, and ability to form hydrogels, making it a suitable candidate for various biomedical applications. • The synthesis of iron oxide magnetic nanoparticles in aqueous solution involves the controlled precipitation of iron salts, followed by their oxidation and subsequent stabilization to prevent agglomeration. • The addition of chitosan biopolymer to the aqueous solution further enhances the stability and dispersibility of the nanoparticles, while also providing additional functional properties. • The synthesized composites have shown promising results in various biomedical applications, including drug delivery, magnetic hyperthermia treatment of cancer, and magnetic resonance imaging (MRI) contrast agents. This study focuses on the synthesis of iron oxide magnetic nanoparticles and their coating with chitosan biopolymer in aqueous solutions. The structural properties of the synthesized nanoparticles were characterized using Fourier Transform Infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), magnetic properties analysis using Vibrating Sample Magnetometry (VSM), and thermal gravimetric analysis (TGA). The FT-IR spectra confirmed the presence of iron oxide and chitosan on the nanoparticle surface. The XRD analysis indicated the crystalline nature of the nanoparticles, and SEM images revealed the morphology and particle size. The VSM results demonstrated the superparamagnetic behavior of the nanoparticles, and TGA analysis showed the thermal stability and decomposition of the nanoparticles. Overall, this synthesis method successfully produced iron oxide magnetic nanoparticles coated with chitosan, which have potential applications in drug delivery systems. [ABSTRACT FROM AUTHOR]