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Primary manifestation of HIV-related Burkitt lymphoma in the oral and maxillofacial regions.
- Source :
-
Journal of the American Dental Association (JADA) . Apr2024, Vol. 155 Issue 4, p344-348. 5p. - Publication Year :
- 2024
-
Abstract
- Burkitt lymphoma (BL) is a subtype of non-Hodgkin lymphoma. It is strongly associated with HIV infection and has a highly aggressive clinical course. The involvement of the maxillofacial region in BL has rarely been reported. A 36-year-old woman with HIV-positive status had painless bilateral swelling of the oral mucosa and middle and lower thirds of the face. Microscopic analysis of the oral lesion revealed an atypical lymphoid infiltrate with a starry sky pattern. The lymphoid cells expressed cluster of differentiation 20, cluster of differentiation 10, B-cell lymphoma 6, and c-Myc; the Ki-67 proliferative index was high. The tumor cells were positive for Epstein-Barr virus. These results led to the diagnosis of HIV-related BL. BL and other immunodeficiency-related lymphoproliferative malignancies may affect the oral and maxillofacial regions and should be included in the differential diagnosis of rapidly expanding swelling in young patients. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00028177
- Volume :
- 155
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of the American Dental Association (JADA)
- Publication Type :
- Academic Journal
- Accession number :
- 176230747
- Full Text :
- https://doi.org/10.1016/j.adaj.2023.11.012