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Temperature-Sensitive Fluorescence Decay Kinetics of Thioflavin T Derivatives in Glycerol.
- Source :
-
Optics & Spectroscopy . Jun2023, Vol. 131 Issue 6, p466-476. 11p. - Publication Year :
- 2023
-
Abstract
- Possible use of Thioflavin T based fluorescent molecular rotors as temperature sensors was assessed in this work. Fluorescent properties of Thioflavin T and its derivative 6-Me-BTA-2C in 99% glycerol were studied using steady-state and time-resolved fluorescence spectroscopy methods. For Thioflavin T in glycerol it has been found that temperature growth from 261 to 353 K results in ~3 orders of magnitude increase of non-radiative decay rate constant knr for the excited state of the molecule. Fluorescence decay studies by time-correlated single photon counting method showed that fluorescence decay kinetics of Thioflavin T in glycerol can be used for temperature measurements in the range 260–290 K. For 6-Me-BTA-2C molecule the range of the maximal sensitivity was shifted to higher temperatures (280–320 K). The obtained results about fluorescent properties and decay kinetics of Thioflavin T based dyes in highly viscous media can be used to develop nanoscale temperature sensors. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0030400X
- Volume :
- 131
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Optics & Spectroscopy
- Publication Type :
- Academic Journal
- Accession number :
- 176300499
- Full Text :
- https://doi.org/10.1134/S0030400X23020212