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A dual-rule encoding DNA storage system using chaotic mapping to control GC content.
- Source :
-
Bioinformatics . Mar2024, Vol. 40 Issue 3, p1-10. 10p. - Publication Year :
- 2024
-
Abstract
- Motivation DNA as a novel storage medium is considered an effective solution to the world's growing demand for information due to its high density and long-lasting reliability. However, early coding schemes ignored the biologically constrained nature of DNA sequences in pursuit of high density, leading to DNA synthesis and sequencing difficulties. This article proposes a novel DNA storage coding scheme. The system encodes half of the binary data using each of the two GC-content complementary encoding rules to obtain a DNA sequence. Results After simulating the encoding of representative document and image file formats, a DNA sequence strictly conforming to biological constraints was obtained, reaching a coding potential of 1.66 bit/nt. In the decoding process, a mechanism to prevent error propagation was introduced. The simulation results demonstrate that by adding Reed-Solomon code, 90% of the data can still be recovered after introducing a 2% error, proving that the proposed DNA storage scheme has high robustness and reliability. Availability and implementation : The source code for the codec scheme of this paper is available at https://github.com/Mooreniah/DNA-dual-rule-rotary-encoding-storage-system-DRRC. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NUCLEOTIDE sequence
*REED-Solomon codes
*DNA
*DNA sequencing
*SOURCE code
Subjects
Details
- Language :
- English
- ISSN :
- 13674803
- Volume :
- 40
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 176301110
- Full Text :
- https://doi.org/10.1093/bioinformatics/btae113