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HFIP promoted cyclization of o-hydroxyaryl enaminones with chlorohydrocarbon for synthesis of chromone-containing triarylmethanes.
- Source :
-
Tetrahedron . Apr2024, Vol. 156, pN.PAG-N.PAG. 1p. - Publication Year :
- 2024
-
Abstract
- A facile and efficient method for the synthesis of chromone-containing triarylmethane derivatives via a HFIP promoted tandem alkylation/annulation protocol of o -hydroxyaryl enaminones with chlorohydrocarbon is described. Employing DCM/HFIP as solvent, the reactions proceed smoothly at room temperature without any transition-metal catalyst, providing a variety of chromone-containing triarylmethanes in moderate to good yields. Moreover, the developed protocol reveals a broad substrate scope and good group tolerance. [Display omitted] [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 156
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 176358205
- Full Text :
- https://doi.org/10.1016/j.tet.2024.133948