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Clinical Comparison between HD-tDCS and tDCS for Improving Upper Limb Motor Function: A Randomized, Double-Blinded, Sham-Controlled Trial.

Authors :
Zeng, Yaqin
Cheng, Ruidong
Zhang, Li
Fang, Shan
Zhang, Shaomin
Wang, Minmin
Lv, Qian
Dai, Yunlan
Gong, Xinyi
Liang, Feng
Source :
Neural Plasticity. 3/31/2024, Vol. 2024, p1-10. 10p.
Publication Year :
2024

Abstract

Background. Stroke is a common and frequently occurring disease among middle-aged and elderly people, with approximately 55%−75% of patients remaining with upper limb dysfunction. How to promote the recovery of motor function at an early stage is crucial to the life of the patient. Objectives. This study aimed to investigate whether high-definition transcranial direct current stimulation (HD-tDCS) of the primary motor cortex (M1) functional area in poststroke patients in the subacute phase is more effective in improving upper limb function than conventional tDCS. Methods. This randomized, sham-controlled clinical trial included 69 patients with subcortical stroke. They were randomly divided into the HD-tDCS, anodal tDCS (a-tDCS), and sham groups. Each group received 20 sessions of stimulation. The patients were assessed using the Action Research Arm Test, Fugl–Meyer score for upper extremities, Motor Function Assessment Scale, and modified Barthel index (MBI) pretreatment and posttreatment. Results. The intragroup comparison scores improved after 4 weeks of treatment. The HD-tDCS group showed a slightly greater, but nonsignificant improvement as compared to a-tDCS group in terms of mean change observed in function of trained items. The MBI score of the HD-tDCS group was maintained up to 8 weeks of follow-up and was higher than that in the a-tDCS group. Conclusion. Both HD-tDCS and a-tDCS can improve upper limb motor function and daily activities of poststroke patients in the subacute stage. This trial is registered with ChiCTR2000031314. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20905904
Volume :
2024
Database :
Academic Search Index
Journal :
Neural Plasticity
Publication Type :
Academic Journal
Accession number :
176363154
Full Text :
https://doi.org/10.1155/2024/2512796