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Does Age Influence Gastrointestinal Status Responses to Exertional-heat Stress?

Authors :
Young, Pascale
Henningsen, Kayla
Snipe, Rhiannon
Gaskell, Stephanie
Alcock, Rebekah
Mika, Alice
Rauch, Christopher
Costa, Ricardo J. S.
Source :
International Journal of Sports Medicine. Apr2024, Vol. 45 Issue 4, p272-281. 10p.
Publication Year :
2024

Abstract

This meta-data exploration aimed to determine the impact of exertional-heat stress (EHS) on gastrointestinal status of masters age and young adult endurance athletes. Sixteen MASTERS (mean: 44y) and twenty-one YOUNG (26y) recreational endurance athletes completed 2 h of running at 60% ˙V O2max in 35˚C ambient conditions. Blood samples were collected pre-, immediately and 1 h post-EHS, and analyzed for markers of exercise-induced gastrointestinal syndrome (EIGS). Thermo-physiological measures and gastrointestinal symptoms (GIS) were recorded every 10–20 min during EHS. Peak Δ pre- to post-EHS did not substantially differ (p>0.05) between MASTERS and YOUNG for intestinal epithelial injury [I-FABP: 1652pg/ml vs. 1524pg/ml, respectively], bacterial endotoxic translocation [sCD14: -0.09µg/mL vs. 0.84µg/mL, respectively], lipopolysaccharide-binding protein [LBP: 0.26µg/mL vs. 1.76µg/mL, respectively], and systemic inflammatory response profile (SIR-Profile: 92.0arb.unit vs. 154arb.unit, respectively). A significantly higher peak Δ pre- to post-EHS in endogenous endotoxin anti-body IgM (p=0.042), and pro-inflammatory cytokine IL-1β (p=0.038), was observed in YOUNG compared to MASTERS. No difference was observed between incidence (81% and 80%, respectively) and severity (summative accumulation: 21 and 30, respectively) of reported GIS during EHS between MASTERS and YOUNG. Pathophysiology of EIGS in response to EHS does not substantially differ with age progression, since masters and younger adult endurance athletes responded comparably. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01724622
Volume :
45
Issue :
4
Database :
Academic Search Index
Journal :
International Journal of Sports Medicine
Publication Type :
Academic Journal
Accession number :
176388781
Full Text :
https://doi.org/10.1055/a-2195-3131