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Evaluating the role of nanoparticles in enhancing bone regeneration in dental implantology.
- Source :
-
Journal of Pharmacy & Bioallied Sciences . 2024 Suppl, Vol. 16, p847-849. 3p. - Publication Year :
- 2024
-
Abstract
- Background: Dental implantology has witnessed substantial progress in recent years, driven by a growing emphasis on optimizing bone regeneration around dental implants. Nanoparticles have emerged as a potential tool for enhancing osseointegration and bone tissue regeneration. Materials and Methods: This human clinical trial enrolled 60 adult participants requiring dental implants. Patients were randomly assigned to one of two groups: a control group receiving conventional dental implants, and an experimental group receiving dental implants with nanoparticle-coated surfaces. Radiographic imaging, histological analysis of bone biopsies, and implant stability assessments were conducted at three and six months post-implantation. Results: Histological examination of bone biopsies revealed a statistically significant increase in new bone formation in the experimental group compared to the control group at both three and six months (P < 0.05). Radiographic assessment demonstrated a 25% higher bone density around nanoparticle-coated implants (P < 0.01) at the six-month mark. Implant stability quotient (ISQ) measurements indicated a 20% greater stability in the experimental group (P < 0.05) at the same time point. Conclusion: This human clinical trial provides strong evidence that the incorporation of nanoparticles on dental implant surfaces enhances bone regeneration and osseointegration in a human population. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09764879
- Volume :
- 16
- Database :
- Academic Search Index
- Journal :
- Journal of Pharmacy & Bioallied Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 176413588
- Full Text :
- https://doi.org/10.4103/jpbs.jpbs_1057_23