尿膜管由来の小細胞神経内分泌癌の一例.

The patient was a 59-year-old woman. She was pointed out to have an intravesical mass at the X-7 year check-up, and was consulted us. Cystoscopy revealed a submucosal mass at the dome of bladder, and MRI revealed a mass at the dome of bladder. She was presented to the Cancer Board with an extravesical mass also considered, but the policy was to follow up the patient as a low malignant lesion. In the X-1 year, he visited previous hospital with cystitis, and CT showed an enlarged mass at the dome of bladder. Because of suspicion of urachal carcinoma, the mass was resected transurethraally and pathological diagnosis was small cell neuroendocrine carcinoma of uroepithelial or urachal origin. According to the treatment strategy for small cell carcinoma of the bladder, the patient was treated with a combination of carboplatin and etoposide as preoperative chemotherapy, followed by total cystectomy and lymph node dissection. The pathological diagnosis of small cell carcinoma of urachal origin was made. Eight months after surgery, local recurrence was observed and combination therapy with cisplatin and etoposide was initiated. The recurrent lesion has partial response and treatment is ongoing. Urachal carcinoma is a disease with poor prognosis because of no established effective regimen. We report here a case of small cell neuroendocrine carcinoma of urachal origin. [ABSTRACT FROM AUTHOR]