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Mpox: An Overview of Pathogenesis, Diagnosis, and Public Health Implications.

Authors :
Branda, Francesco
Romano, Chiara
Ciccozzi, Massimo
Giovanetti, Marta
Scarpa, Fabio
Ciccozzi, Alessandra
Maruotti, Antonello
Source :
Journal of Clinical Medicine. Apr2024, Vol. 13 Issue 8, p2234. 13p.
Publication Year :
2024

Abstract

Mpox, caused by viruses of the genus Orthopoxvirus, is an emerging threat to human and animal health. With increasing urbanization and more frequent interaction between humans and wild animals, the risk of Mpox transmission to humans has increased significantly. This review aims to examine in depth the epidemiology, pathogenesis, and diagnosis of Mpox, with a special focus on recent discoveries and advances in understanding the disease. Molecular mechanisms involved in viral replication will be examined, as well as risk factors associated with interspecific transmission and spread of the disease in human populations. Currently available diagnostic methods will also be discussed, with a critical analysis of their limitations and possible future directions for improving the accuracy and timeliness of diagnosis. Finally, this review will explore the public health implications associated with Mpox, emphasizing the importance of epidemiological surveillance, vaccination, and emergency preparedness to prevent and manage possible outbreaks. Understanding the epidemiology and control strategies for Mpox is critical to protecting the health of human and animal communities and mitigating the risk of interspecific transmission and spread of the disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20770383
Volume :
13
Issue :
8
Database :
Academic Search Index
Journal :
Journal of Clinical Medicine
Publication Type :
Academic Journal
Accession number :
176876282
Full Text :
https://doi.org/10.3390/jcm13082234