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T-cell Defects in a Patient with NFKBIA Gene Mutation.
- Source :
-
Journal of Clinical Immunology . Jun2024, Vol. 44 Issue 5, p1-4. 4p. - Publication Year :
- 2024
-
Abstract
- This letter, published in the Journal of Clinical Immunology, discusses a case study of a patient with an NFKBIA gene mutation, which is associated with an immunodeficiency disease called anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID). The patient exhibited various clinical manifestations, including ectodermal dysplasia, recurrent infections, and autoimmune diseases. The study found that the NFKBIA gene mutation led to defective T-cell function, as evidenced by impaired T-cell proliferation and cytokine production. The authors suggest that this research contributes to a better understanding of the role of the NFKBIA gene in T-cell function and highlights the need for further study in this area. [Extracted from the article]
- Subjects :
- *GENETIC mutation
*T cells
Subjects
Details
- Language :
- English
- ISSN :
- 02719142
- Volume :
- 44
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Clinical Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 176910442
- Full Text :
- https://doi.org/10.1007/s10875-024-01703-y