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Efficient removal of uranium from the kidneys by a picolinate-based pentadentate chelator.
- Source :
-
New Journal of Chemistry . 5/7/2024, Vol. 48 Issue 17, p7552-7556. 5p. - Publication Year :
- 2024
-
Abstract
- In conjunction with theoretical calculations, the in vitro and in vivo uranyl binding capabilities of a bidentate picolinate (Pic) ligand and its pentadentate derivative (H2dpa) are investigated. The planar N3O2-donor configuration of H2dpa matches the typical pentagonal-bipyramid coordination geometry of uranyl, demonstrating a remarkable removal preference for uranyl in the kidneys. [ABSTRACT FROM AUTHOR]
- Subjects :
- *KIDNEYS
*URANIUM
*GEOMETRY
*LIGAND binding (Biochemistry)
Subjects
Details
- Language :
- English
- ISSN :
- 11440546
- Volume :
- 48
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- New Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 176911895
- Full Text :
- https://doi.org/10.1039/d4nj00986j