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More than meets the eye: A conserved sensorimotor reflex helps unravel the circuit mechanisms of ASD.

Authors :
Hyde, Romana J.
Rudolph, Stephanie
Source :
Neuron. May2024, Vol. 112 Issue 9, p1375-1378. 4p.
Publication Year :
2024

Abstract

Animal models are instrumental to understanding the mechanisms underlying autism spectrum disorder, yet translating human behavioral phenotypes remains challenging. Wang et al. leverage a conserved sensorimotor reflex to elucidate synaptic deficits in S cn2a haploinsufficiency and pilot novel rescue strategies. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
08966273
Volume :
112
Issue :
9
Database :
Academic Search Index
Journal :
Neuron
Publication Type :
Academic Journal
Accession number :
176954592
Full Text :
https://doi.org/10.1016/j.neuron.2024.04.003