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Sifting for Gold in Terabytes of Data: Illuminating Cardiovascular Biology in the ‘Omics Age.

Authors :
Shah, Svati H.
Gerszten, Robert E.
Source :
Circulation. 4/23/2024, Vol. 149 Issue 17, p1323-1325. 3p.
Publication Year :
2024

Abstract

This article discusses the use of 'omics' data, such as genomics, proteomics, and metabolomics, in cardiovascular biology research. The article highlights the shift towards a human-forward approach, where large-scale data is generated from human samples to gain mechanistic insights, identify disease risk, and discover new therapeutic targets. However, the translation of these costly experiments into biomarkers or therapeutics for patient care has been limited. The article emphasizes the need for interdisciplinary team science, better bioinformatics, and time to bridge the gap between 'omics' discovery and clinical application. [Extracted from the article]

Details

Language :
English
ISSN :
00097322
Volume :
149
Issue :
17
Database :
Academic Search Index
Journal :
Circulation
Publication Type :
Academic Journal
Accession number :
176957202
Full Text :
https://doi.org/10.1161/CIRCULATIONAHA.123.066988