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Hypoglossal nerve delineation in nasopharyngeal carcinoma patients may reduce the radiation dose and damage to the nerve.
- Source :
-
Medical Dosimetry . Summer2024, Vol. 49 Issue 2, p102-108. 7p. - Publication Year :
- 2024
-
Abstract
- This study aims to establish a delineation guideline for the contouring of the hypoglossal nerve by dividing the nerve into different segments, and to test the possibility of a radiation dose reduction to the hypoglossal nerve in NPC patients receiving radiotherapy. Twenty NPC patients were selected arbitrarily. The hypoglossal nerves were delineated using anatomic landmarks and divided into the cisternal, intracanalicular, carotid, and transverse segments. The tumor coverage by radiation and dose-volume parameters of the nerve with and without various dose constraints to the hypoglossal nerve were compared. The hypoglossal nerve, which is invisible on CT images, can be delineated accurately with the assistance of several anatomic landmarks. Without a dose constraint to the hypoglossal nerve, the carotid space, intracanalicular, and transverse segments had high radiation dose-volumes. The dose-volume to the nerve, however, can be reduced when the nerve was defined and a dose constraint was given. The delineation of the hypoglossal nerve with its different segments is feasible. The carotid space, intracanalicular, and transverse segments received the highest dose, where the nerve damage was most likely located. The dose to the nerve can be reduced to less than 70 Gy using the intensity-modulated radiotherapy technique. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09583947
- Volume :
- 49
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Medical Dosimetry
- Publication Type :
- Academic Journal
- Accession number :
- 177036289
- Full Text :
- https://doi.org/10.1016/j.meddos.2023.09.001