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Biopolymer based nanoparticles and their therapeutic potential in wound healing – A review.

Authors :
Kumar, Mohit
Mahmood, Syed
Chopra, Shruti
Bhatia, Amit
Source :
International Journal of Biological Macromolecules. May2024:Part 2, Vol. 267, pN.PAG-N.PAG. 1p.
Publication Year :
2024

Abstract

Nanoparticles (NPs) have been extensively investigated for their potential in nanomedicine. There is a significant level of enthusiasm about the potential of NPs to bring out a transformative impact on modern healthcare. NPs can serve as effective wound dressings or delivery vehicles due to their antibacterial and pro-wound-healing properties. Biopolymer-based NPs can be manufactured using various food-grade biopolymers, such as proteins, polysaccharides, and synthetic polymers, each offering distinct properties suitable for different applications which include collagen, polycaprolactone, chitosan, alginate, and polylactic acid, etc. Their biodegradable and biocompatible nature renders them ideal nanomaterials for applications in wound healing. Additionally, the nanofibers containing biopolymer-based NPs have shown excellent anti-bacterial and wound healing activity like silver NPs. These NPs represent a paradigm shift in wound healing therapies, offering targeted and personalized solutions for enhanced tissue regeneration and accelerated wound closure. The current review focuses on biopolymer NPs with their applications in wound healing. [Display omitted] [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01418130
Volume :
267
Database :
Academic Search Index
Journal :
International Journal of Biological Macromolecules
Publication Type :
Academic Journal
Accession number :
177036403
Full Text :
https://doi.org/10.1016/j.ijbiomac.2024.131335