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Acid‐Catalyzed Ring Opening Reaction of Cyclopropyl Carbinols with Acetonitrile to Synthesize Amides.
- Source :
-
ChemistrySelect . 5/3/2024, Vol. 9 Issue 17, p1-4. 4p. - Publication Year :
- 2024
-
Abstract
- A one‐pot protocol for the synthesis of amides has been developed by employing acetonitrile as nitrogen source and solvent. The reaction undergoes ring‐opening of cyclopropyl carbinols and in situ formation of homoallylic carbocation, which reacts with acetonitrile to give desired products. The substrate of this reaction is widely applicable and the desired products are obtained in moderate to good yields. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ACETONITRILE
*AMIDES
*RING-opening reactions
*CARBOCATIONS
Subjects
Details
- Language :
- English
- ISSN :
- 23656549
- Volume :
- 9
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- ChemistrySelect
- Publication Type :
- Academic Journal
- Accession number :
- 177040204
- Full Text :
- https://doi.org/10.1002/slct.202305039