CAR T-Cell Therapy in Autoimmune Disease.

The article focuses on the contrasting outcomes of CAR T-cell therapy in patients with systemic lupus erythematosus (SLE) and systemic sclerosis, highlighting prompt clinical and serologic remission in SLE patients but less complete remission in systemic sclerosis patients, suggesting that CAR T-cell therapy efficacy may vary based on autoimmune condition and emphasizing the need for tailored approaches rather than a universal solution.