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A systematic review of the management of eosinophilic dermatosis of hematological malignancy.

Authors :
Tan, Stephanie
Choong, Dean Jeremy
Tan, Ernest
Source :
International Journal of Dermatology. May2024, p1. 8p. 1 Illustration, 1 Chart.
Publication Year :
2024

Abstract

Eosinophilic dermatosis of hematologic malignancy (EDHM) is a cutaneous manifestation seen in patients with hematoproliferative and lymphoproliferative disorders, most commonly chronic lymphocytic leukemia. This systematic review aimed to summarize the therapeutic interventions of EDHM. A comprehensive search yielded 71 studies, predominantly case reports and series. The most frequently reported modalities were systemic and topical corticosteroids, as well as treatment of the underlying malignancy. Responses to these treatments varied. Targeted therapies, including dupilumab and omalizumab, showed promise, as did other modalities such as montelukast, dapsone, doxycycline, and phototherapy. Higher‐quality studies should be conducted to facilitate higher‐quality management recommendations for EDHM. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00119059
Database :
Academic Search Index
Journal :
International Journal of Dermatology
Publication Type :
Academic Journal
Accession number :
177124262
Full Text :
https://doi.org/10.1111/ijd.17221