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Multicomponent Click Reaction: An Indispensable Tool for Easy Access of Functionalized 1,2,3‐Triazoles.

Authors :
Yadav, Mangal S.
Rajkhowa, Sanchayita
Singh, Sumit K.
Jaiswal, Manoj K.
Tiwari, Vinod K.
Source :
ChemistrySelect. 5/13/2024, Vol. 9 Issue 18, p1-30. 30p.
Publication Year :
2024

Abstract

Multicomponent reactions are operationally simple and display a significant role in diverse chemical modification by reducing reaction times as well as additional steps involved. In this review, we highlighted the impact of multi‐component reactions in assistance with modular Click chemistry to develop a library of triazole‐appended scaffolds including 1,2,3‐triazole‐fused heterocycles, glycoconjugates, macrocycles as well as in the combinatorial synthesis of differently functionalized triazoles along with mechanistic insights with a diverse range of applications in the field of medicinal chemistry. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23656549
Volume :
9
Issue :
18
Database :
Academic Search Index
Journal :
ChemistrySelect
Publication Type :
Academic Journal
Accession number :
177193409
Full Text :
https://doi.org/10.1002/slct.202400776