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Haemorrhagic stroke and brain vascular malformations in women: risk factors and clinical features.

Authors :
Ali, Mariam
van Etten, Ellis S
Akoudad, Saloua
Schaafsma, Joanna D
Visser, Marieke C
Ali, Mahsoem
Cordonnier, Charlotte
Sandset, Else Charlotte
Klijn, Catharina J M
Ruigrok, Ynte M
Wermer, Marieke J H
Source :
Lancet Neurology. Jun2024, Vol. 23 Issue 6, p625-635. 11p.
Publication Year :
2024

Abstract

Haemorrhagic stroke is a severe condition with poor prognosis. Biological sex influences the risk factors, presentations, treatment, and patient outcomes of intracerebral haemorrhage, aneurysmal subarachnoid haemorrhage, and vascular malformations. Women are usually older at onset of intracerebral haemorrhage compared with men but have an increased risk of aneurysmal subarachnoid haemorrhage as they age. Female-specific factors such as pregnancy, eclampsia or pre-eclampsia, postmenopausal status, and hormone therapy influence a woman's long-term risk of haemorrhagic stroke. The presence of intracranial aneurysms, arteriovenous malformations, or cavernous malformations poses unique clinical dilemmas during pregnancy and delivery. In the absence of evidence-based guidelines for managing the low yet uncertain risk of haemorrhagic stroke during pregnancy and delivery in women with vascular malformations, multidisciplinary teams should carefully assess the risks and benefits of delivery methods for these patients. Health-care providers should recognise and address the challenges that women might have to confront when recovering from haemorrhagic stroke. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14744422
Volume :
23
Issue :
6
Database :
Academic Search Index
Journal :
Lancet Neurology
Publication Type :
Academic Journal
Accession number :
177223218
Full Text :
https://doi.org/10.1016/S1474-4422(24)00122-4