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Clinical Insights: Antimicrobial Therapy for Infectious Uveitis.

Authors :
Leong, Evangeline
Cifuentes-González, Carlos
Hu Y. W., Jeremy
Perumal Samy, Ramar
Khairallah, Moncef
Rojas-Carabali, William
Putera, Ikhwanuliman
de-la-Torre, Alejandra
Agrawal, Rupesh
Source :
Ocular Immunology & Inflammation. May2024, p1-21. 21p. 1 Illustration, 7 Charts.
Publication Year :
2024

Abstract

Infectious uveitis is a major global cause of vision impairment. Despite the eye’s immune privilege, afforded by the blood-ocular barrier that restricts microbial entry, several pathogens such as bacteria, viruses, fungi, and parasites can still infiltrate and cause ocular infections and complications. Clinicians often encounter significant challenges in treating infectious uveitis due to limited or ineffective treatment options. Modern molecular techniques and imaging can aid in diagnosing and assessing intraocular infections. Various antimicrobial therapies exist, spanning topical and systemic treatments, but these are constrained by issues like drug concentration, penetration, effective duration, toxicity, and side effects. Treatment approaches also differ based on the infection’s etiology. This review provides recent updates on antimicrobial therapies from a clinical perspective, covering topical, systemic, and regional treatments for infectious uveitis. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09273948
Database :
Academic Search Index
Journal :
Ocular Immunology & Inflammation
Publication Type :
Academic Journal
Accession number :
177269778
Full Text :
https://doi.org/10.1080/09273948.2024.2345848