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Characteristics of VE/HXLPE wear particle morphology: A comparative analysis with UHMWPE in an in vitro artificial tibial insert simulation test.
- Source :
-
Wear . Jun2024, Vol. 548, pN.PAG-N.PAG. 1p. - Publication Year :
- 2024
-
Abstract
- Particle generation from artificial knee prostheses is a leading cause of artificial joint failures. Vitamin E stabilized highly cross-linked polyethylene (VE/HXLPE) is known for its antioxidant properties and minimal wear characteristics. However, research on the wear behavior of VE/HXLPE is limited. This study aims to compare wear debris from VE/HXLPE with the conventional material Ultra High Molecular Weight Polyethylene (UHMWPE) under identical in vitro test conditions. Specifically, Principal Component Analysis (PCA) was employed to morphologically categorize particles, resulting in four distinct groups for VE/HXLPE and five for UHMWPE. Notably, 68 % of VE/HXLPE particles exhibited small-sized spheroidal morphology, while UHMWPE mainly produced elongated bioactive particles. Key particle attributes were then assessed, including 'equivalent circle diameter (ECD)', 'aspect ratio (AR)', and 'roundness (R) ', and presented as frequency distributions. The morphological analysis revealed that VE/HXLPE particles displayed various shapes, such as spheroidal, flakes, bulks, rods, and fibrils, and their formation mechanism was discussed. Additionally, the Functional Biological Activity (FBA) of VE/HXLPE wear particles was calculated. The results demonstrated differences in particle sizes, shape distributions, and bioactivity between VE/HXLPE and UHMWPE, which indicates that VE/HXLPE particles had a lower likelihood of inducing osteolysis. This study holds promise for gaining deeper insights into the mechanical properties and the potential for bioactivity in VE/HXLPE as an artificial joint material. • The comparison of morphology of VE/HXLPE and UHMWPE tibial debris from an in vitro test. • The distributions of size and shape and their comprehensive morphologic clustering by the principal component method. • Prediction of bioactivity of osteolysis caused by the VE/HXLPE and UHMWPE debris. • The typical shapes of the isolated debris and their wear mechanism. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00431648
- Volume :
- 548
- Database :
- Academic Search Index
- Journal :
- Wear
- Publication Type :
- Academic Journal
- Accession number :
- 177290361
- Full Text :
- https://doi.org/10.1016/j.wear.2024.205390