瘢痕疙瘩术后联合放疗的疗效观察及复发因素分析.

Objective To investigate the efficacy of keloid surgery combined with radiation therapy (radiotherapy) and the effects of surgical approach, the start time of radiotherapy, the dose of radiotherapy, the site of keloid growth, and whether or not to apply a medical silicone gel dressing (Barnes ＆ Noble) on keloid recurrence. Methods A total of 45 patients with keloid who admitted to the hospital from January 2020 to July 2021 were retrospectively analyzed and divided into the group A (surgery combined with conventional radiotherapy, 10 cases),the group B (surgery combined with macrodissected radiotherapy, 12 cases),group C (surgery alone, eight cases),and group D (surgery combined with Barnes ＆ Noble treatment, 15 cases) according to the different treatment modalities. The treatment modalities, clinical efficacy and recurrence factors of the four groups were retrospectively analyzed. Results There were two cases of recurrence in patients in group A (20. 00%),one case of recurrence in patients in group B (8. 33%),seven cases of recurrence in patients in group C (87. 50%),and 13 cases of recurrence in patients in group D (86. 67%) . The efficacy of surgery combined with radiotherapy was significantly better than that of the group without postoperative radiotherapy, and the difference was statistically significant (P＜0. 05) . Whether or not postoperative combined radiotherapy was the main influencing factor of keloid recurrence. Conclusion Compared with the non-radiotherapy group, surgery combined with radiotherapy can significantly increase the cure rate and decrease the recurrence rate of patients; whether or not to combine radiotherapy after surgery, and whether or not the scar is in the joint mobility area are the high-risk factors for keloid recurrence. [ABSTRACT FROM AUTHOR]