Electrochemically polymerized dopamine activated carbon paste sensor for selective and sensitive detection of rutin in the presence of riboflavin.

[Display omitted] • A poly(dopamine) modified carbon paste electrode was designed to detect rutin (RT) using voltammetric technique. • The DA film increased the sensitivity of the bare electrode towards RT, the electrocatalytic activity of the sensor was confirmed by CV and EIS study. • The PDAMCPE follows adsorption-controlled process during the electrochemical reaction of RT. • The modified electrode exhibited good repeatability, reproducibility and stability. • PDAMCPE showed good recovery rate when examined in real samples like green tea and tablet sample. In this work, a sensor was developed for the quantification of RT in food and medicine samples using electro-polymerization of dopamine (DA) on the surface of a carbon paste electrode in 0.2 M phosphate buffered saline (PBS) of 7.0 pH by cyclic voltammetry (CV). The surface properties of bare carbon paste electrode (BCPE) and poly (DA) modified carbon paste electrode (PDAMCPE) were studied using scanning electron microscopy (SEM), electrochemical impedance study (EIS), and CV techniques. Two electron two proton transfer process was seen during the electrochemical reaction of RT with adsorption-controlled process. Under optimum conditions, the peak current increased linearly with an increase in RT concentration for CV in the range of 0.4 to 2.0 μM and differential pulse voltammetry (DPV) in the range of 0.4 to 2.5 μM and the limit of detection (LOD) was found to be 0.0045 μΜ and for CV and 0.079 μM for DPV techniques respectively. Even in the presence of some interferents like organic compounds and metal ions, the developed electrode exhibits good anti-interference ability for RT, and good selectivity was obtained for RT in the presence of riboflavin (RF). The developed sensor presents good stability, repeatability, and reproducibility. The CV measurement was performed for the analysis of RT in real samples such as green tea and medicine samples which showed a good recovery and this work has been not reported previously. [ABSTRACT FROM AUTHOR]