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Visualization of Risk Factors and Predictive Models for Early Death of Neonatal Gastric Perforation.

Authors :
Mengying, Cui
Pengfei, Chen
Jinfeng, Hou
Yi, Wang
Wei, Liu
Zhenhua, Guo
Source :
Clinical Pediatrics. Jul2024, Vol. 63 Issue 7, p986-994. 9p.
Publication Year :
2024

Abstract

A retrospective analysis was performed from May 2003 to October 2021 at our hospital. One hundred and eleven neonates diagnosed with gastric perforation were categorized into non-survivor and survivor groups based on prognosis. The mortality rate was 23.42%. Logistic regression was used to analyze the factors influencing the early neonatal death. The non-survivor groups showed more abdominal distension, vomiting, hypoxia, acidosis, hyperkalemia, and coagulation abnormalities. Serum potassium concentration (odds ratio [OR] 2.148, P =.043) was an independent risk factor; however, arterial partial pressure of oxygen (OR 0.977, P =.024), bicarbonate (OR 0.779, P =.023), and platelet count (OR 0.986, P =.014) had protective effects on neonatal death. Based on this, a visualized nomogram prediction model was constructed, patients who had a nomogram score of more than 163.787 was considered to have high risks of mortality, the area under the curve of this was up to 0.828 (95% confidence interval [0.733, 0.923]), the sensitivity was 80.0%, and the specificity was 76.9%. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00099228
Volume :
63
Issue :
7
Database :
Academic Search Index
Journal :
Clinical Pediatrics
Publication Type :
Academic Journal
Accession number :
177461491
Full Text :
https://doi.org/10.1177/00099228231201315