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Transgene‐free CRISPR/Cas9‐mediated gene editing through protoplast‐to‐plant regeneration enhances active compounds in Salvia miltiorrhiza.
- Source :
-
Plant Biotechnology Journal . Jun2024, Vol. 22 Issue 6, p1549-1551. 3p. - Publication Year :
- 2024
-
Abstract
- This article discusses a study on gene editing in Salvia miltiorrhiza, a plant used in Eastern medicine to treat cardiovascular diseases. The researchers developed a protoplast regeneration system for S. miltiorrhiza using CRISPR/Cas9 gene editing technology. They targeted seven transcription factor genes involved in the production of bioactive compounds in the plant. The study demonstrated high-efficiency gene editing and the regeneration of knockout plants, which could potentially enhance the contents of active compounds in medicinal plants. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 14677644
- Volume :
- 22
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Plant Biotechnology Journal
- Publication Type :
- Academic Journal
- Accession number :
- 177466602
- Full Text :
- https://doi.org/10.1111/pbi.14285