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Perspectives in the treatment of interstitial lung disease accompanied with anti‐melanoma differentiation‐associated gene 5‐positive dermatomyositis.

Authors :
Tsuji, Hideaki
Nakashima, Ran
Mimori, Tsuneyo
Source :
International Journal of Rheumatic Diseases. May2024, Vol. 27 Issue 5, p1-4. 4p.
Publication Year :
2024

Abstract

This article discusses the treatment of interstitial lung disease (ILD) accompanied by anti-melanoma differentiation-associated gene 5 (MDA5)-positive dermatomyositis. The early diagnosis of ILD is crucial due to its rapid progression and life-threatening nature. Treatment options include Janus kinase (JAK) inhibitors, plasmapheresis, and triple immunosuppressive therapy with glucocorticoids, calcineurin inhibitors, and intravenous cyclophosphamide. The article emphasizes the importance of careful monitoring for infections and adverse events during intensive immunosuppressive treatments. The efficacy of these treatments is supported by growing evidence, although further research is needed. [Extracted from the article]

Details

Language :
English
ISSN :
17561841
Volume :
27
Issue :
5
Database :
Academic Search Index
Journal :
International Journal of Rheumatic Diseases
Publication Type :
Academic Journal
Accession number :
177482270
Full Text :
https://doi.org/10.1111/1756-185X.15201