Uraemia with imbalanced calcium phosphorus metabolism on [68Ga]Ga-FAPI versus [18F]F-FDG PET/CT.

This article discusses a case study of a 35-year-old man with a history of uraemia who presented with increased tumor marker levels. The patient underwent both [18F]F-FDG PET/CT and [68 Ga]Ga-FAPI-04 total-body PET/CT scans. The [18F]F-FDG PET/CT showed increased FDG uptake in osteogenic destructive bones and extensive calcification, while the [68 Ga]Ga-FAPI-04 PET/CT revealed FAPI uptake in the same lesions as well as additional abnormal foci. The study suggests that FAPI PET/CT may be superior to FDG PET/CT in diagnosing and assessing kidney fibrosis and related calcium phosphorus metabolism disorders in chronic kidney disease. [Extracted from the article]