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Snoring-generated fluid droplets as a potential mechanistic link between sleep-disordered breathing and pneumonia.
- Source :
-
Respiratory Research . 5/29/2024, Vol. 25 Issue 1, p1-4. 4p. - Publication Year :
- 2024
-
Abstract
- The soft palate and back of the throat represent vulnerable early infection sites for SARS-CoV-2, influenza, streptococci, and many other pathogens. We demonstrate that snoring causes aerosolization of pharyngeal fluid that covers these surfaces, which previously has escaped detection because the inspired airstream carries the micron-sized droplets into the lung, inaccessible to traditional aerosol detectors. While many of these droplets will settle in the lower respiratory tract, a fraction of the respirable smallest droplets remains airborne and can be detected in exhaled breath. We distinguished these exhaled droplets from those generated by the underlying breathing activity by using a chemical tracer, thereby proving their existence. The direct transfer of pharyngeal fluids and their pathogens into the deep lung by snoring represents a plausible mechanistic link between the previously recognized association between sleep-disordered breathing and pneumonia incidence. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SLEEP apnea syndromes
*SOFT palate
*PNEUMONIA
*FLUIDS
*SNORING
Subjects
Details
- Language :
- English
- ISSN :
- 14659921
- Volume :
- 25
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Respiratory Research
- Publication Type :
- Academic Journal
- Accession number :
- 177559087
- Full Text :
- https://doi.org/10.1186/s12931-024-02856-5