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Evaluating the Risk Index for Serious Prescription Opioid-Induced Respiratory Depression or Overdose in Patients with Cancer.
- Source :
-
Journal of Pain & Palliative Care Pharmacotherapy . Jun2024, Vol. 38 Issue 2, p131-137. 7p. - Publication Year :
- 2024
-
Abstract
- The Commercially Insured health Plan Risk Index for Overdose or Serious Opioid-induced Respiratory Depression (CIP-RIOSORD) is an evidence-based tool to determine serious opioid-induced respiratory depression (OIRD) or overdose risk. The CIP-RIOSORD total score determines a risk class and estimates the probability for an OIRD event within the next 6 months. We performed a single-center, retrospective analysis to determine CIP-RIOSORD baseline scores and the most common predictive factors in patients with cancer. Patients (n = 160) were split into new consultations (n = 83, Group 1) versus the first documented follow-up consultation (n = 77, Group 2). Most patients were Caucasian women with metastatic gastrointestinal cancer. CIP-RIOSORD scores for Group 1 patients were 14.8 ± 15.2 (mean ± SD, risk class 4). Group 2 patients had higher CIP-RIOSORD scores (16.6 ± 14.9, risk class 4). For Group 1, the most common CIP-RIOSORD predictive factors were use of a long-acting opioid formulation (n = 24, 29%) and daily oral morphine equivalent (OME) ≥100 (n = 20, 24%); for Group 2, predictive factors were use of an antidepressant (n = 34, 44%) and a long-acting opioid formulation (n = 27, 35%). Based on the CIP-RIOSORD, there is a 15% probability of experiencing a serious OIRD event or overdose within the next 6 months. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RESPIRATORY disease risk factors
*DRUG overdose
*RISK assessment
*GASTROINTESTINAL tumors
*MORPHINE
*HEALTH insurance
*PROBABILITY theory
*RESPIRATORY diseases
*OPIOID abuse
*CANCER patients
*RETROSPECTIVE studies
*METASTASIS
*ANTIDEPRESSANTS
*OPIOID analgesics
*MEDICAL records
*ACQUISITION of data
*DRUGS
*DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 15360288
- Volume :
- 38
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Pain & Palliative Care Pharmacotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 177713798
- Full Text :
- https://doi.org/10.1080/15360288.2024.2348620