Response to Letter to the Editor.

This document is a response to a letter to the editor regarding a study on the relationship between skeletal muscle and lower urinary tract symptoms (LUTS) in older men. The authors agree that the relationship between skeletal muscle and LUTS is complex and potentially bidirectional. They also acknowledge the co-occurrence of LUTS and poor sleep, which may accelerate biological aging mechanisms and worsen the functional impact of LUTS. The authors express skepticism about the proposed role of testosterone in this relationship and suggest that other factors, such as decreased mobility and physical activity, may play a more significant role. They propose further research to identify and test plausible conceptual models and interventions to improve symptom burden and functional status in older men with LUTS. The study was supported by various grants and the authors declare no conflicts of interest. [Extracted from the article]