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Validation of the Italian version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS) in an Italian Parkinson's disease cohort.

Authors :
Maggi, Gianpaolo
Vitale, Carmine
Giacobbe, Chiara
Barone, Angelo
Mastromarino, Clara
Iannotta, Federica
Amboni, Marianna
Weintraub, Daniel
Santangelo, Gabriella
Source :
Neurological Sciences. Jul2024, Vol. 45 Issue 7, p3153-3161. 9p.
Publication Year :
2024

Abstract

Introduction: Impulse control disorders (ICDs) frequently occur in Parkinson's disease (PD), and an early identification is essential to prevent severe psychosocial consequences. The Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease–Rating Scale (QUIP-RS) has been developed to evaluate the severity of ICDs along with a range of impulsive-compulsive behaviors (ICBs) in PD; however, its Italian version has not yet been validated. Methods: One hundred consecutive outpatients with PD were administered an Italian version of the QUIP-RS and a brief neuropsychological assessment to evaluate global cognitive status and scales to measure depression, apathy and impulsive disorders. We evaluated the internal consistency, convergent and divergent validity, and factorial structure of QUIP-RS. We also explored the possible association between QUIP-RS scores and clinical factors and dopaminergic medication. Results: Subsyndromal ICDs manifestations were observed in 54% of the patients, and one in four (22%) reported two or more ICDs or related behaviors. The QUIP-RS demonstrated good internal consistency (Cronbach's alpha = 0.806) and construct validity, and its factorial structure reflected different ICDs and ICBs domains. No association emerged between QUIP-RS scores and the clinical aspects of PD and dopaminergic medication. Conclusion: We provided, for the first time, an Italian translation of the QUIP-RS and demonstrated its feasibility in clinical and research settings. Severity of ICDs was independent of clinical factors and dopaminergic medication, underlining the need to adopt a broader perspective on their etiopathology in PD. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15901874
Volume :
45
Issue :
7
Database :
Academic Search Index
Journal :
Neurological Sciences
Publication Type :
Academic Journal
Accession number :
177879540
Full Text :
https://doi.org/10.1007/s10072-024-07304-2