A Prospective Randomized Study to Evaluate if Cyanoacrylate Glue is Superior over Traditional Suturing in Laparoscopic Port Site Skin Closure.

Background: This study was undertaken to evaluate if the cyanoacrylate glue was superior to conventional suturing for skin closure of the laparoscopic port site. A prospective randomized trial was performed on patients scheduled for elective laparoscopic surgery at the department of general surgery at a tertiary care hospital. Patients were followed up to evaluate postoperative pain using the visual analog scale (VAS). The time required for closing the wound, postoperative pain at the wound site, rate of surgical site infection (SSI), and the period for which the patients stayed in the hospital were studied. Results: A total of 70 patients were enrolled and divided into two groups. In group I (the study group) incisions were closed by applying N-Butyl-2-Cyanoacrylate glue and in group II (the control group) incisions were closed by conventional suturing method using Ethilon 2.0 RC. Statistically significant difference was found between the average time required for the closure of a single port site (p < 0.0001), surgical site infection (p < 0.021), and the average number of days the patient stayed in the hospital. It was less in the group I as compared with that of group II. There was no significant difference between the two groups for postoperative pain assessment. Conclusion: The use of N-Butyl-2-Cyanoacrylate at laparoscopic port site skin closure was beneficial as it took comparatively less time for laparoscopic port skin closure and had less rate of surgical site infection at the wound site. [ABSTRACT FROM AUTHOR]