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Pharmaceutical Emulsions: A Viable Approach for Ocular Drug Delivery.

Authors :
Bisen, Amol Chhatrapati
Srivastava, Saurabh
Mishra, Anjali
Sanap, Sachin Nashik
Biswas, Arpon
Choudhury, Abhijit Deb
Dubey, Ayush
Gupta, Neeraj Mohan
Yadav, Karan Singh
Mugale, Madhav Nilakanth
Bhatta, Rabi Sankar
Source :
Journal of Ocular Pharmacology & Therapeutics. Jun2024, Vol. 40 Issue 5, p261-280. 20p.
Publication Year :
2024

Abstract

Ocular disorders can lead to serious sight impairment and irreversible blindness. Generally simple topical and systemic treatments are recommended for treating these vision-threatening illnesses. The distinctive architecture of the eye complicates ocular drug delivery. The ophthalmic emulsion formulations have been found to increase bioavailability in the eye by prolonging residence time and improving permeability through the cornea. Therefore, this study highlights ophthalmic emulsions meant for both the anterior and posterior parts of the eye while examining a wide range of ocular disorders that affect individuals globally. This review presents, in brief, recent emulsion-based patented innovations, clinical trials, and marketed emulsion formulations for ocular drug delivery, which are strengthening development of the new ophthalmic drug products for managing different ocular diseases and disorders. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10807683
Volume :
40
Issue :
5
Database :
Academic Search Index
Journal :
Journal of Ocular Pharmacology & Therapeutics
Publication Type :
Academic Journal
Accession number :
177948217
Full Text :
https://doi.org/10.1089/jop.2023.0166