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Clinical utility of the at-risk for psychosis state beyond transition: A multidimensional network analysis.
- Source :
-
European Child & Adolescent Psychiatry . Jun2024, p1-10. - Publication Year :
- 2024
-
Abstract
- To be relevant to healthcare systems, the clinical high risk for psychosis (CHR-P) concept should denote a specific (i.e., unique) clinical population and provide useful information to guide the choice of intervention. The current study applied network analyses to examine the clinical specificities of CHR-P youths compared to general help-seekers and non–CHR-P youth. 146 CHR-P (mean age = 14.32 years) and 103 non–CHR-P (mean age = 12.58 years) help-seeking youth were recruited from a neuropsychiatric unit and assessed using the Structured Interview for Psychosis-Risk Syndromes, Children’s Depression Inventory, Multidimensional Anxiety Scale for Children, Global Functioning: Social, Global Functioning: Role, and Wechsler Intelligence Scale for Children/Wechsler Adult Intelligence Scale. The first network structure comprised the entire help-seeking sample (i.e., help-seekers network), the second only CHR-P patients (i.e., CHR-P network), and the third only non–CHR-P patients (i.e., non–CHR-P network). In the help-seekers network, each variable presented at least one edge. In the CHR-P network, two isolated “archipelagos of symptoms” were identified: (a) a subgraph including functioning, anxiety, depressive, negative, disorganization, and general symptoms; and (b) a subgraph including positive symptoms and the intelligence quotient. In the non–CHR-P network, positive symptoms were negatively connected to functioning, disorganization, and negative symptoms. Positive symptoms were less connected in the CHR-P network, indicating a need for specific interventions alongside those treating comorbid disorders. The findings suggest specific clinical characteristics of CHR-P youth to guide the development of tailored interventions, thereby supporting the clinical utility of the CHR-P concept. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10188827
- Database :
- Academic Search Index
- Journal :
- European Child & Adolescent Psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 177959822
- Full Text :
- https://doi.org/10.1007/s00787-024-02491-x