Reply to Glycemic Index/Load Effect on ALS Progression: Potential Interaction with Riluzole.

A recently published article titled "Higher Glycemic Index and Glycemic Load Diet Is Associated with Slower Disease Progression in Amyotrophic Lateral Sclerosis" found a significant association between dietary glycemic index (GI) and glycemic load (GL) with functional decline and survival in patients with amyotrophic lateral sclerosis (ALS). However, questions have been raised about the potential interaction between riluzole intake, the most commonly used medication for ALS patients, and the association between GI/GL and disease progression. The authors plan to analyze the dataset further to examine whether dietary GI or GL have different associations with functional decline and survival among those with or without riluzole intake. The authors have no conflicts of interest related to the product discussed in the study. [Extracted from the article]