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小窝蛋白1在肝脏疾病中的调控作用.

Authors :
朱骏毅
李瑞蕊
舒仪雪
孙 泉
Source :
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi. Jun2024, Vol. 40 Issue 6, p1269-1274. 6p.
Publication Year :
2024

Abstract

Caveolin-1 (CAV1) is a structural protein of caveolae on the plasma membrane and is an important regulatory factor for liver function. CAV1 regulates hepatic lipid deposition, lipid and glucose metabolism, mitochondrial function, and hepatocyte proliferation through various molecular pathways. Therefore, CAV1 plays a crucial role in maintaining liver physiology during the metabolic regulatory processes such as hepatic steatosis and hepatocyte proliferation. Furthermore, CAV1 is also involved in the development and progression of different types of liver injury, hepatitis, and liver cirrhosis. This article reviews the role of CAV1 in liver-related diseases and its mechanism in the regulation of liver macrophages, so as to provide a theoretical basis for targeting CAV1 in the treatment of liver-related diseases. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
10015256
Volume :
40
Issue :
6
Database :
Academic Search Index
Journal :
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi
Publication Type :
Academic Journal
Accession number :
178012274
Full Text :
https://doi.org/10.12449/JCH240631