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Issue Information.

Source :
Journal of Neurochemistry. Jul2024, Vol. 168 Issue 7, p1173-1174. 2p.
Publication Year :
2024

Abstract

This article, titled "The role of age‐associated alpha‐synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation," explores the development of a transgenic mouse model to study the role of α‐synuclein (α‐syn) in the progression of Parkinson's disease (PD). The study found that at 9 months of age, significant α‐syn aggregation was observed in dopaminergic neurons, highlighting the importance of age-associated accumulation of α‐syn aggregates in PD progression. The findings suggest a potential mechanism for the development of Lewy bodies in PD. The full article can be accessed for further information. [Extracted from the article]

Details

Language :
English
ISSN :
00223042
Volume :
168
Issue :
7
Database :
Academic Search Index
Journal :
Journal of Neurochemistry
Publication Type :
Academic Journal
Accession number :
178021303
Full Text :
https://doi.org/10.1111/jnc.15859