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Strategic framework for harnessing luminescent metal nanocluster assemblies in biosensing applications.
- Source :
-
Analytical & Bioanalytical Chemistry . Jul2024, Vol. 416 Issue 17, p3963-3974. 12p. - Publication Year :
- 2024
-
Abstract
- The distinctive physicochemical attributes of ultra-small metal nanoclusters (MNCs) resembling those of molecules make them versatile constituents for self-assembled frameworks. This critical review scrutinizes the influence of assembly on the photoluminescence (PL) properties of MNCs and investigates their utility in biosensing applications. The investigation is initiated with an assessment of the shift from individual MNCs to assemblies and its repercussions on PL efficacy. Subsequently, two distinct biosensing modalities are explored: assembly-driven detection mechanisms and detection predicated on structural modifications in assembled MNCs. Through meticulous examination, we underscore the potential of self-assembly methodologies in tailoring the PL behavior of MNCs for the detection of diverse biological analytes and diseases. [ABSTRACT FROM AUTHOR]
- Subjects :
- *METALS
*PHOTOLUMINESCENCE
Subjects
Details
- Language :
- English
- ISSN :
- 16182642
- Volume :
- 416
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Analytical & Bioanalytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 178029436
- Full Text :
- https://doi.org/10.1007/s00216-024-05353-2