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Predictors for Recurrence of Cytomegalovirus Retinitis in HIV-Negative Patients.
- Source :
-
Ocular Immunology & Inflammation . Jul2024, Vol. 32 Issue 5, p493-500. 8p. - Publication Year :
- 2024
-
Abstract
- To investigate the incidence of and predictive factors for recurrent cytomegalovirus retinitis (CMVR) in human immunodeficiency virus (HIV)-negative patients. A retrospective review of HIV-negative patients who were newly diagnosed with CMVR between January 2005 and February 2019. Of 28 patients (44 eyes), 35.9% of eyes had a recurrence of CMVR after discontinuation of anti-CMV therapy. The incidence of CMVR recurrence was 17 per 100 eye-years. The factors significantly associated with CMVR recurrence were eyes with retinitis area of more than 25% (P =.013), absence of vitreous haze (P =.003), neutropenia at presentation (P =.001), and absence of systemic immunosuppression therapy prior to presentation (P =.002). Eyes with a large area of retinitis, absence of vitreous haze, and neutropenia at presentation are predictive of CMVR recurrence while receiving systemic immunosuppression prior to CMVR presentation has a lower risk of CMVR recurrence. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HIV
*CYTOMEGALOVIRUSES
Subjects
Details
- Language :
- English
- ISSN :
- 09273948
- Volume :
- 32
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Ocular Immunology & Inflammation
- Publication Type :
- Academic Journal
- Accession number :
- 178176315
- Full Text :
- https://doi.org/10.1080/09273948.2023.2170250